Depression & Mental Health Treatment in Springfield, Massachusetts

Welcome to Cambridge Biotherapies in Springfield

At Cambridge Biotherapies, we understand that finding effective treatment for depression can be a difficult journey. We are a premier destination for those seeking innovative mental health treatment in the heart of Massachusetts. We provide advanced, patient-centered care for depression, anxiety, and other mood disorders, and our team is dedicated to providing compassionate, effective care in a safe and private setting.

Our expert team, led by a Harvard-trained psychiatrist and Chief Medical Officer, has helped over 1,000 patients find relief from severe depression. Our advanced treatments have been shown to improve symptoms in over 70% of cases, even for those who have not responded to traditional medications and psychotherapy.

Our Advanced Treatments for Depression

We offer a range of FDA-approved and innovative therapies designed to provide rapid and profound relief. Our Springfield location provides Ketamine Therapy, Spravato (Esketamine), and TMS (Transcranial Magnetic Stimulation) treatments.

Ketamine Therapy for Depression

Ketamine therapy provides rapid relief for many individuals, particularly those with treatment-resistant depression or PTSD. It works chemically to address the brain areas most commonly associated with depressive disorders. We offer IV Ketamine infusions and Ketamine-Assisted Psychotherapy (KAP).

Spravato® (Esketamine) Nasal Spray

Spravato is an FDA-approved nasal spray that offers rapid relief from depression for individuals who have not had success with at least two other antidepressants. We administer it in a certified medical office under professional supervision.

TMS Therapy for Depression

Transcranial Magnetic Stimulation (TMS) is an FDA-approved, non-invasive treatment that uses magnetic fields to stimulate nerve cells in the brain to improve symptoms of depression. We believe TMS is a great option for patients who cannot tolerate the side effects of medications or have not found them to be effective.

Frequently Asked Questions

How does Ketamine therapy work?
We use Ketamine because it affects NMDA receptors in the brain to provide a rapid antidepressant effect. We administer it in a controlled medical setting with a trained professional and monitor your vital signs.
What are the side effects of Ketamine?
Most of our patients tolerate Ketamine well, often feeling sleepy or relaxed. Some may experience visual changes, nausea, or a temporary increase in blood pressure. We closely monitor these effects, and they typically subside quickly.
Is Ketamine covered by insurance?
Insurance coverage for IV Ketamine is evolving. While the initial consultation may be covered, the infusions often require pre-payment, with billing submitted to your insurance for reimbursement. We can help you navigate this process.
How does Spravato® work?
Spravato contains esketamine, which targets a different neurotransmitter pathway than traditional antidepressants, leading to faster results. We use it in conjunction with a daily oral antidepressant to maximize benefits.
What does the Spravato® treatment process involve?
You will self-administer the nasal spray at our clinic, and we will monitor you for two hours to ensure your safety and comfort. During this time, you can relax under the care of our team.
What are the side effects of Spravato®?
Common side effects can include dizziness, nausea, dissociation (feeling disconnected from your thoughts), and temporary sedation. These effects are temporary and usually subside within a few hours.
How many TMS Therapy sessions do I need?
A typical course of treatment at our clinic consists of five sessions per week over a period of four to six weeks.
How long do the effects from TMS Therapy last?
TMS is considered a durable treatment, with some of our patients experiencing sustained relief for up to one year or longer. We may recommend maintenance sessions to prolong the effects.
What should I expect during a TMS Therapy session?
During a TMS session, you will be awake and in a comfortable chair while we place a device on your head. Each session takes approximately 20-40 minutes, and you can resume your daily activities immediately after.

Meet Our Team

Our Springfield team includes a carefully selected staff of psychiatrists, therapists, nurses, and support staff dedicated to providing the highest level of care. We believe that expertise and compassion are key to a successful treatment journey.

Why Choose Cambridge Biotherapies?

  • Expert, Compassionate Care: We believe in a patient-centered approach to treatment, ensuring you feel heard and supported throughout your journey.
  • Advanced, Effective Treatments: We offer cutting-edge therapies that are proven to be effective for even the most difficult-to-treat cases of depression.
  • Trust and Transparency: We are committed to helping you understand your condition and treatment options. We provide clear, honest information so you can make informed decisions about your health.
  • Local Community Focus: We are located in the heart of downtown Springfield at 1550 Main St., Suite 108. Our clinic is near local landmarks like Springfield College and Baystate Medical Center, with convenient parking nearby.

Client Reviews

Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
After thirty plus years of therapy and medication this work has changed my life. Everyone at Cambridge Biotherapies clearly loves what they do, participating in a healing process that brings about such unprecedented and positive outcomes. I am so grateful that I was able to do this work in this place with these people.
Posted on Google Google
Lisa Block
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
Okay, I never write Google reviews, or any reviews, but Cambridge Biotherapies deserves one. I cannot say enough positive things about my experience there. They quite literally saved my life. The whole team goes above and beyond. Everyone in the facility is so wonderful - kind, warm, welcoming, educated, and highly competent. The nurses are very well-versed and always show up with a perfect balance of medical professionalism and holding safe, compassionate space. Every time I've asked the nurse for support during treatment, they have shown up for me exactly as I needed. The rooms are comfortable, the lighting is soothing, the chairs are perfect, and the provided tools - weighted blankets, eye masks, headphones, music - make for an even more effective treatment. As a person with severe medical trauma, I have felt so safe with the treatment methods. In addition to excellent mental health awareness, all staff members seem to specifically be very trauma-informed. I feel so comfortable sharing my needs and they meet them without fail. Set and setting are everything for a treatment such as this, and Cambridge Biotherapies cultivates those beautifully. I want to give an extra shout-out to Catherine here - she is probably the sweetest person I have ever met and her warmth and care immediately make me feel so safe when I walk in the door. I am so grateful to this facility. I have my life back.
Posted on Google Google
Nic Parkhurst
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
I recommend doing the KAP assisted therapy. Odessa the therapist was great and Char and Katherine in the office are awesome! My depression feels lessened after a couple of sessions.
Posted on Google Google
April Ford
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
This center offers a warm, cozy and friendly environment with expert providers who are willing to spend time establishing rapport, learning your history and recommending the best protocol that will meet your individual needs to achieve relief and recovery.
Posted on Google Google
Angela Babuschak
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
Amazing staff, very knowledgeable, caring and supportive.
Posted on Google Google
Georgiy Victoria Nikitin
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
I received ketamine treatments here for most of 2020, and they changed my life. It was like someone had released the pressure in my brain, and I was able to rebuild from there. The doctors, nurses, techs and other employees were kind and friendly. The facility itself is more like a home setting than a cold and clinical one, but still sterile enough that I felt very safe there even through the start of the pandemic. They really want you to be comfortable during the treatments and will work hard to accommodate individual needs. I’d definitely return if it wasn’t so expensive, but I do not hold the cost of treatment against the clinic itself.
Posted on Google Google
Rachel Schlow
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
Amazing staff. The people here really care and they have the knowledge to back up their treatments. You know you’re getting what’s best for you when you’re here.
Posted on Google Google
Sanjay Talluri
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
After trying everything else for twenty years, and finding nothing worked, I found Cambridge Bio therapies. I have done both TMS and Ketamine infusion with very good results. There is hope here and it does get better. So if you are depressed or having PTSD, or both...you should try this. Even if you tried everything else; this, is different, and unlike other means, works quickly.
Posted on Google Google
Dianne Sawtelle
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
Caring, Kind, Effective
Posted on Google Google
Linda Morgan

Take the First Step Now

Location

We are located in the heart of downtown Springfield at 1550 Main St., Suite 108, close to local transit routes and accessible from surrounding neighborhoods and nearby medical facilities. The clinic is within reach of Springfield College, Baystate Medical Center, and other key community landmarks. Parking options are available nearby for your convenience.

Accessibility

  • Fully wheelchair accessible
  • Service animal friendly

Emergencies

Please be aware that our Cambridge Biotherapies™ team is only available during business hours and is not equipped to handle medical emergencies. If you or someone you know is in crisis, please contact your provider, dial 911, or reach out to the National Suicide Prevention Lifeline at 1-800-273-8255.