Accelerated TMS Therapy

A new, accelerated, and more effective TMS treatment at Cambridge Biotherapies.

An eight-week protocol for TMS is already approved by the FDA for the treatment of depression. However, a recent study at Stanford University, entitled Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression (SAINT-TRD) demonstrated that when TMS was delivered in a more intensive schedule and accelerated pace, it provided remission from depression in 86% of patients in as little as 3 to 5 days. These results were published online April 7, 2020 in the American Journal of Psychiatry.
Accelerated TMS Therapy at Cambridge Biotherapies - Anxiety and Depression Relief

Cambridge Biotherapies now offers such an accelerated brain stimulation treatment for depression.

In the Stanford study, patients underwent 10 sessions per day of 10-minute treatments, with 50-minute breaks between treatments. Each treatment was an extended version of the currently FDA-approved “Theta Burst” TMS, which requires specialized equipment to deliver. On average, three days of the therapy were enough for participants to experience relief from depression. One study participant’s mood score indicated she was no longer depressed after a single day of treatment, while it took up to five days for other participants to achieve remission.

How Safe is Accelerated TMS Therapy?

The only side effects of this new, rapid TMS approach were fatigue and some discomfort during treatment.

Of particular note: In order to test safety, the researchers evaluated the participants’ cognitive function before and after treatment. They found no negative side effects. Instead, they discovered that the participants’ ability to switch between mental tasks and to solve problems had improved — a typical outcome for people who are no longer depressed. And one month after the therapy, 60% of participants were still in remission from depression.

Our Approach to Accelerated TMS

At Cambridge Biotherapies we are able to treat patients using precisely the same parameters used in the Stanford study. The only difference in our approach is that we use an FDA-approved, office-based method of finding the treatment location, called direct brain mapping, rather than MRI. And for patients with anxiety, we offer the option of concurrent treatment with a theta burst TMS protocol directed toward alleviation of those symptoms as well.

We have begun treating patients using the Stanford SAINT protocol at Cambridge Biotherapies, and our initial experience with accelerated TMS has led us to feel optimistic that this new treatment approach represents a paradigm shift in TMS therapy, with potential substantial benefits to patients with depression.

Call to Get Started with Accelerated TMS Therapy

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